Irg1 acod1
WebFeb 26, 2024 · Also known as CAD; Irg1 Summary Enables aconitate decarboxylase activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of defense response; and negative regulation of signal transduction. Acts upstream of or within response to lipopolysaccharide. Located in mitochondrion. WebFeb 12, 2024 · Aconitate decarboxylase 1 (ACOD1, also known as immunoresponsive gene 1 [IRG1]) is a key regulator of immunometabolism during infection and inflammation.[20,21,22] It was first discovered in 1992 as a lipopolysaccharide (LPS)- inducible gene in murine macrophages.[] Later, metabolomics profiling analyses revealed that ACOD1 is …
Irg1 acod1
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WebApr 15, 2024 · 1. Introduction. Itaconate was first isolated from Aspergillus terreus and has been utilized in industrial processes for decades as a precursor to polymer synthesis [1,2].Recent surprising findings have revealed that itaconate is produced in activated macrophages and that aconitate decarboxylase 1 (Acod1, also known as immune … WebRoseville, MI. $25. AM/FM radio vintage/antique 50’s . West Bloomfield, MI. $25. Vintage 1994 Joe’s Place 4 Plastics Cups & 1991 Hard Pack 5 Different Camel Characters Lighters …
WebListed are ELISA Kits for the detection of IRG1, an alias name of aconitate decarboxylase 1. The human protein, encoded by the gene ACOD1, is 481 amino acid residues long and has a mass of 52,628 daltons. It is a member of the PrpD family. This protein is reported to have a mitochondrial cellular localization.
WebMar 15, 2024 · IRG1 encodes an aconitate decarboxylase (ACOD1) that produces the immunomodulatory metabolite itaconate (ITA). In addition to rapid intracellular accumulation, ITA is also secreted from the cell, but whether secreted ITA functions as a signaling molecule is unclear. Here, we identified ITA as an orthosteric agonist of the … WebACOD1 in immunometabolism and disease. Immunometabolism plays a fundamental role in health and diseases and involves multiple genes and signals. Aconitate decarboxylase 1 …
WebSep 16, 2024 · The pathogenic mechanisms of cardiorenal syndrome type 4 (CRS4) remain unclear. Here, the authors identify IRF1-PGC1α axis-mediated myocardial energy …
WebJun 2, 2024 · Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism callaway maverick head coversWeb产品图片 产品编号 品牌 cas号 产品名称 分子式 购物车 coat park lifeWebFeb 10, 2024 · The immunoresponsive gene 1 (Irg-1), also known as Acod1, was first identified as a 2.3-kb cDNA from a murine macrophage cell line stimulated with lipopolysaccharide (LPS) . callaway maverick head coverWeb丁香通为您提供MouseACOD1Ir商品详情介绍：价格：询价，货号：EM2074，品牌：FineTest，产地：湖北武汉，详见丁香通MouseACOD1Ir商品详情页； callaway maverick golf ironsWebFeb 8, 2024 · Irg1 transcript induction was achieved by adding the histone deacetylase (HDAC) inhibitor valproic acid (VPA) to a histidine-tryptophan-ketoglutarate solution used … callaway maverick irons loftsWebSep 21, 2024 · Recently, some studies have shown that immune responsive gene 1 (IRG1, also called ACOD1) was upregulated significantly by IFN-γ or LPS stimuli. 6 IRG1 is an enzyme that catalyzes the production of itaconate by decarboxylating cis-aconitate, which inhibits microorganism replication through itaconate and reactive oxygen species (ROS). … callaway maverick golf clubs reviewsWebNational Center for Biotechnology Information coat park schuhe