WebGenetic factors that cause insulin resistance: Genes can affect the ability of the pancreas to produce sufficient insulin. It may also affect the body’s ability to respond to insulin. Genetic tendency to accumulate fat in the abdomen (abdominal obesity) can contribute to insulin resistance and hence make a person more likely to develop diabetes. WebAug 28, 2024 · Type 1 diabetes (T1D) is a chronic autoimmune disorder that leads to progressive pancreatic ß-cell destruction and culminates in absolute insulin deficiency and stable hyperglycaemia. It is very likely that environmental factors play a role in triggering islet autoimmunity. Knowing whether they have true relevance in favoring T1D …
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