Cral-trio domain-containing protein

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August undefined, 2024

WebThe motile sperm domain-containing protein 2 (MSPD2) is found at membrane contact sites of the ER, in which it is anchored by its C-terminal TM helix. It engages lipid droplets via its CRAL-TRIO domain, which specifically recognizes packing defects and negatively charged phospholipids . This ... WebThe bipartite CRAL_TRIO motif is composed of a large lobe encoding a hydrophobic lipid-binding pocket (CRAL_TRIO_C) that is closed off by a smaller N-terminal lobe (CRAL_TRIO_N) . To analyze the lipid-binding activity of CPSFL1, we used recombinant affinity-purified Sec14 proteins and performed protein−lipid blot overlay assays ( Fig. 5 A ...

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WebCRAL/TRIO domain containing protein (AHRD V1 **-- B6U4K1_MAIZE); contains Interpro domain(s) IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal Gene … WebDi Mattia et al. (2024) noted that human MOSPD2 is a 518-amino acid protein containing an N-terminal CRAL/TRIO domain, a major sperm protein (MSP) domain, and a potential C-terminal transmembrane domain. A GFP-tagged MOSPD2 was localized to the ER of transfected HeLa cells, and mutation analysis showed that MOSPD2 was anchored to … blissy contact number

Phylogenetic analysis of plant multi-domain SEC14-like ...

WebJul 1, 2015 · Here, we discovered that a plant protein-coding gene containing the CRAL_TRIO domain serves as a promoter in bacteria. We firstly characterized CitPITP1 from Citrus, which contains the CRAL_TRIO domain, and identified a 64-bp sequence (key64) that is critical for prokaryotic promoter activity. In vitro experiments indicated that … WebID: PRUN2_MOUSE DESCRIPTION: RecName: Full=Protein prune homolog 2; AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1; FUNCTION: May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). DEVELOPMENTAL … WebSep 11, 2024 · One protein family with membrane recognition and signaling properties is the SEC14-like phosphatidylinositol transfer protein (SEC14L-PITP) superfamily. SEC14L-PITPs, first identified in yeast (Saccharomyces cerevisiae) by screening for secretory mutants, share their characteristic SEC14 domain, also known as CRAL-TRIO domain … free ach transfer api

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YPIBP: A repository for phosphoinositide-binding proteins in yeast

WebMay 15, 2010 · The activation of the protein kinase Raf at the cell membrane is a critical step in cell signaling during development, but the mechanisms that regulate Raf activity … WebNov 1, 2024 · CRAL_TRIO family proteins are cytosolic and contain the SEC14 carboxy-terminal domain [7, 9]. The CRAL_TRIO subgroup derives its name from the cellular … free achievement certificatesWebSep 1, 2009 · 3.40.525.10 CRAL-TRIO lipid binding domain 1 hit; 1.20.900.10 Dbl homology (DH) domain 2 hits; ... PTHR22826:SF106 DH DOMAIN-CONTAINING PROTEIN 1 hit; PTHR22826 RHO GUANINE EXCHANGE FACTOR-RELATED 1 hit; PROSITE. View protein in PROSITE; PS50191 CRAL_TRIO 1 hit; PS50010 DH_2 2 … blissy gift card

"WebMutations in another protein containing a CRAL-TRIO domain, alpha-tocopherol transfer protein (TTPA), cause a vitamin E-responsive ataxia. Three-dimensional protein structural modeling predicts that the caytaxin ligand is more polar than vitamin E. Identification of the caytaxin ligand may help develop a therapy for Cayman ataxia. " - Cral-trio domain-containing protein

Cral-trio domain-containing protein

MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; MOSPD2

WebExplore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest. … WebCRAL-TRIO domain-containing protein YKL091C. Status. UniProtKB reviewed (Swiss-Prot) Organism. Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's …

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WebSep 29, 2024 · Drawing: All Atoms Virtual Bond. Aligned Rows: up to 5 up to 10 up to 20 up to 40 up to 60 All 95 rows. Download Cn3D. PubMed References. pfam00650 is … WebMar 27, 2012 · The CRAL_TRIO protein domain, which is unique to the Sec14 protein superfamily, binds to a diverse set of small lipophilic ligands. Similar domains are found in a range of different proteins including neurofibromatosis type-1, a Ras GTPase-activating Protein (RasGAP) and Rho guanine nucleotide exchange factors (RhoGEFs). Proteins …

WebThe CRAL_TRIO protein domain, which is unique to the Sec14 protein superfamily, binds to a diverse set of small lipophilic ligands. Similar domains are found in a range of different proteins including neurofibromatosis type-1, a Ras GTPase- ... Identification of BCH and CRAL_TRIO domain containing proteins from the GenBank database The protein ... WebCRAL-TRIO domain is a protein structural domain that binds small lipophilic molecules. This domain is named after cellular retinaldehyde-binding protein (CRALBP) and TRIO …

WebMay 15, 2010 · The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation Introduction. Cell fates are established during development by spatially … CRAL-TRIO domain is a protein structural domain that binds small lipophilic molecules. This domain is named after cellular retinaldehyde-binding protein (CRALBP) and TRIO guanine exchange factor. CRALB protein carries 11-cis-retinol or 11-cis-retinaldehyde. It modulates interaction of retinoids with … See more The Sec14 protein was the first CRAL-TRIO domain for which the structure was determined. The structure contains several alpha helices as well as a beta sheet composed of 6 strands. Strands 2,3,4 and 5 form a parallel … See more C20orf121; MOSPD2; PTPN9; RLBP1; RLBP1L1; RLBP1L2; SEC14L1; SEC14L2; SEC14L3; SEC14L4; TTPA; See more • UMich Orientation of Proteins in Membranes families/superfamily-129 - Calculated spatial positions of CRAL-TRIO domains in membrane See more

WebExplore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest. There are 7 hidden Markov models representing the CRAL/TRIO domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match …

WebThe CRAL_TRIO protein domain, which is unique to the Sec14 protein superfamily, binds to a diverse set of small lipophilic ligands. Similar domains are found in a range of different proteins including neurofibromatosis type-1, a Ras GTPase-activating Protein (RasGAP) and Rho guanine nucleotide exchange factors (RhoGEFs). blissy face maskWebJun 24, 2024 · Second, one type of CRAL-TRIO domain (PF03765) is enriched in the binding proteins of PtdIns and PI4P, ... Moreover, a CRAL-TRIO domain-containing plant protein, patellin1 (PatL1), has been shown to bind to PI4P and PI(4,5)P2 . Whether CRAL-TRIO domain can bind PI4P and PI(4,5)P2 in yeast is worth investigating further. free acid techno samplesWeb2.1. 3D modeling and sequence logo of the insect CRAL_TRIO/SEC14 domain The three-dimensional protein structure of the SEC14 domain (containing the CRAL_TRIO domain) was predicted using I-TASSER (Roy et al., 2010), which uses both multiple threading alignments and ab initio modeling with further reﬁnement to obtain the most likely 3D … blissy face masks ukWebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … free acknod bikesWebLOC4338246 CRAL-TRIO domain-containing protein C589.09, mitochondrial [ Oryza sativa Japonica Group (Japanese rice) ] Gene ID: 4338246, updated on 2-Mar-2024. Download Datasets Summary. Go to the top of the page Help. Gene symbol LOC4338246 Gene description CRAL-TRIO domain-containing protein C589.09, mitochondrial ... free ach paymentsWebProteins containing the Sec14 domain, also referred to as the CRAL-TRIO domain, are found throughout Eukarya. Sec14 domains bind a sing le lipophilic molecule with the … free acid reflux diet planWebDescription: Homo sapiens motile sperm domain containing 2 (MOSPD2), transcript variant 2, mRNA. ... SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential). SIMILARITY: Contains 1 CRAL-TRIO domain. SIMILARITY: Contains 1 MSP domain. Primer design for this transcript free acls course online